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Fear altering parasites

 
 
otto628
02:36 / 04.04.07
Hi,

I lurk this forum every now and again.

I've always had an interest in neuroscience having partaken in Neurofeedback myself as a means to treat ADHD.

I found this article regarding the Toxoplasma gondii parasite to be fascinating.

This parasite impacts a rat's innate ability to feel fear when it detects cat urine.

When exposed to this parasite, rats are known to become -attracted- towards cat urine as opposed to being repelled by it(which I guess would be instinctual for any sort of rat/mouse/gerbil)

What really got to me was how this parasite not only impacted the rats ability to feel fear towards the smell of cat urine, it impacted --only-- that.

In other words, rats would still feel fear towards other things that rats are normally afraid of....

a new study shows the parasite..........seems to target a rat's fear of cat urine with almost surgical precision, leaving other kinds of fear alone.


The article can be found ...here.

This whole topic got me wondering how this parasite could evolve so.

Then I kinda flipped things around and started thinking back to what little I knew of Howard Bloom's work (Lucifer's Hammer I believe).

His work, and please correct me if I'm wrong, is about how humans and other animals are really just giant condominiums for bacteria, proteins, enzymes, and peptides.

How our behaviour, on many levels(individually, societally, etc...) are governed at this microscopic level.
 
 
grant
17:04 / 04.04.07
Toxoplasmosis has also been implicated in schizophrenia -- apparently some anti-schizophrenia drugs also work as anti-Toxoplasma drugs, while Toxoplasmosis sufferers... lemme just quote the article I quoted elsewhere:

Infection with the parasite has been associated with damage to a certain class of neurons (astrocytes). So has schizophrenia. Pregnant women with high levels of Toxoplasma antibodies in their blood were more likely to give birth to children who would later develop schizophrenia.
 
 
otto628
02:06 / 06.04.07
This thread is giving me a desire to read both Howard Bloom's "Lucifer's Hammer" as well as Red Queen by Matt Ridley

Makes me wonder how much we are driven by our bacteria, enzymes, proteins, etc..........
 
 
Sunfell
19:07 / 18.04.07
That toxoplasmosis can change a rats' natural behavior in order to facilitate its spread is not surprising. I think that we've just barely scratched the surface where our interaction with biological parasites is concerned. For example, I've read more than a few articles which link our ultra clean environment to the incredible rise in allergic reactions.

Modern Hygiene's Dirty Tricks

While raising barricades against deadly scourges, however, the industrialized world has also shielded people from the microbes and parasites that do no harm. Does it matter?

A growing number of scientists now suspect that stamping out these innocuous organisms is weakening some parts of children's immune systems, allowing other parts to grow unchecked. Such an imbalance, they theorize, triggers a host of illnesses, including asthma, allergies, and even such autoimmune diseases as rheumatoid arthritis and the most severe type of diabetes.

This notion, called the hygiene hypothesis, arose from scientists' inability to explain the rising prevalence of asthma and allergies in many developed nations. The National Heart, Lung, and Blood Institute estimates that in the United States, for example, the incidence of asthma is now 1.75 times what it was in 1980, and for children less than 4 years old, 2.60 times the earlier incidence.


The whole subject of parasitology fascinates me. Maybe playing in the dirt as a kid wasn't such a bad thing after all.

[dang it, y'all need a blockquote format ability...]
 
  
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