quote:Originally posted by Mordant Carnival:
L.S.D. is soluble in fat. If a person uses acid heavily over time, L.S.D. will be laid down as the body stores fat over time.
WRONG.
Here's the scoop:
quote:http://www.erowid.org/chemicals/lsd/lsd_myth1.shtml/ There is an often circulated myth that once you have taken LSD, it remains in your body forever. The main thing that keeps these rumors circulating the is fact that some people (though very few) experience "flashbacks" (generally within a few months after a hallucinogenic experience). It is generally accepted, however, that these flashbacks are not the result of lsd remaining in the system.
LSD is almost entirely metabolized within a day after ingestion. Since the half-life of LSD is only a few hours, only a very small amount of LSD remains even at the end of the trip, and this is excreted in the urine.
(excerpted)
From Psychedelics Encyclopedia :
LSD is a very curious chemical. When given by injection, it disappears rapidly from the blood. It can be observed when tagged with Carbon 14 in all the tissues, particularly the liver, spleen, kidneys, and adrenal glands. The concentration found in the brain is lower than in any other organ -- being only about 0.01 percent of the administered dose. [...]
LSD is highly active when administered orally, absorbed through mucous membranes or through the skin, and is almost completely absorbed by the gastrointestinal tract. Concentrations in the organs reach peak values after only ten to fifteen minutes; then they decrease very rapidly. [...] Some 80 percent of injested LSD is excreted via the liver, bile system and intestinal tract, with only about 8 percent appearing in uring. After two hours, only 1 to 10 percent is still present in the form of unchanged LSD; the rest consists of water soluble metabolites -- such as 2-oxo-2,3-dihydro-LSD -- which do not possess any LSD-type influence on the central nervous system.
Psychic effects of LSD reach their peak about one to three hours following ingestion, when much of the substance has disappeared from the body's major organs, including the brain, though measurable amounts persist in the blood and brain for about eight hours.
From the DEA Web Site :
LSD is absorbed easily from the gastrointestinal tract, and rapidly reaches a high concentration in the blood. It is circulated throughout the body and, subsequently, to the brain. LSD is metabolized in the liver and is excreted in the urine in about 24 hours.
From Pharmacotheon :
The drug is almost completely eliminated from the body before the peak effects begin, suggesting that it acts as a sort of catalyst, inducing neurochemical changes which subsequently result in the entheogenic experience. Only about 1-10% of injected LSD is excreted unaltered, the remainder as a variety of degradation products.
From Psychedelic Drugs Reconsidered :
The half-life of LSD in blood plasma is about two hours.
References :
Grinspoon, Lester and James B. Bakalar. Psychedelic Drugs Reconsidered. 1997. pg 14.
Hofmann, Albert. LSD My Problem Child. 1979. pg 27.
Ott, Jonathon. Pharmacotheon. 1993. pg 128.
Stafford, Peter. Psychedelics Encyclopedia. 1992. pg 69.
In summation:
- water soluble.
- leaves the system almost entirely *before* the user starts "peaking".
- byproducts and metabolites gone in two days.
[ 20-07-2001: Message edited by: grant ] |
