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Gene Therapy, Age, Organ Repair

 
 
We're The Great Old Ones Now
15:04 / 08.10.03
Gene Therapy:

British scientists are to pioneer the development of gene therapy for chronic and incurable conditions by announcing the first clinical trials on the eye and brain beginning next year.

On-the-spot repairs for damaged and disfunctional organs. Excellent! Does it have longer-term implications? Are we looking at a therapy which will eventually form part of what is effectively a regime of anti-aging treatments?

A search at New Scientist will give you (among other things) the following news items:

Tissue engineers regrow penis - with feeling
Fish's regrown heart gives hope for humans
Face transplants 'possible within a year'

Science appears to be going far faster than society is coming up with paradigms for dealing with these situations. There are organisations for ethics in science, but nothing out there seems able to tell us what this means or how to deal with any of it...

I know a very smart C of E vicar. The other day I asked him what he felt about cloning. He looked surprised that I would ask.

"I've no problem with a clone," he said. "I'm worried about the person who caused it to be made, because it strikes me they may be beset by the sin of vanity."

If only everyone say it so simply...

Are we heading for Identity/Culture shock? (Again?)
 
 
Thjatsi
03:10 / 14.10.03
I have to admit that I am very excited about the prospect of gene therapy. However, it still needs more work. In the US, many of the gene therapy trials were temporarily suspended a few months ago, because two children contracted cancer, which was potentially caused by the treatment.

For treating aging, I'm more excited about the insulin and insulin-like pathways. Basically, inhibitors of these pathways lead to an increase in lifespan for yeast, nematodes, fruit flies, and now mice. Some of the researchers in this field are forming drug companies, so they can begin to look for inhibitors of the insulin-like pathway. If you're going to make bets on aging treatments for the near future, I think this is the way to go.
 
  
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